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Trombofilia ereditară apare datorită prezenței unor anomalii genetice, care intervin în sinteza unor proteine cu rol în coagluare. Cele mai des întâlnite forme sunt: factorul V Leiden; mutaţiile genei protrombinei. Rareori pot fi întâlnite si。

Trombofilia reprezinta o afectiune care se manifesta prin tendinta de coagulare a sangelui la nivel intravascular. Cheagurile de sange formate pot determina aparitia trombozei venoase profunde sau a trombembolismului。

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